A Natural Supplement for Degenerative Diseases of the Central Nervous System
Unlock the potential of a natural supplement designed to support individuals suffering from degenerative diseases of the central nervous system, such as Parkinson's disease. Mannitol has shown promise in helping reduce symptoms and improve the quality of life for those affected by these challenging conditions.
Do you find yourself relying on an increasing number of medications to manage your condition?
If so, here’s some crucial information you should know:
Medications do not address the underlying cause of Parkinson's disease; they only treat the symptoms.
The true culprit is a protein called alpha-synuclein.
This protein is abundant in the human brain and gradually destroys the brain cells responsible for producing dopamine, a key chemical that sends signals to other parts of the brain to regulate movement, coordination, and certain cognitive functions.
New research has uncovered a potential solution to the problem of alpha-synuclein clumps.
Scientists have identified a molecule capable of preventing and reducing the formation of alpha-synuclein aggregates. That molecule is mannitol!
This natural treatment for Parkinson's has shown promising results, with studies indicating that mannitol can reduce the formation of these aggregates by approximately 70%.
Discover This Unique Mannitol Formula:
Homeotreat has developed a distinctive mannitol powder that combines the natural sweetener derived from vegetables like onions, pumpkin, seaweed, and mushrooms. This formula not only helps reduce the production of the alpha-synuclein protein but also includes the Mucuna plant, which supports the enhancement of essential components for healthy brain function.
This unique Mannitol formula can help alleviate the symptoms of this challenging disease.
Mannitol serves various purposes; it is commonly used to reduce elevated pressure in the brain (central edema) and in the eyes. Approved by both the FDA and EFSA, Mannitol is a low-calorie sweetener that offers a natural alternative to sugar.
It is particularly beneficial for individuals with Parkinson's disease, as it has been shown to be a contributory factor in managing symptoms while also serving as a sugar substitute for those with diabetes or anyone pursuing a healthier lifestyle by reducing processed sugar intake.
In Parkinson's disease, nerve damage in the brain is often associated with the crystallization of alpha-synuclein protein. Studies indicate that mannitol can reduce the formation of these aggregates by approximately 70%. Additionally, the velvet bean, or Mucuna, is a rich and readily available source of dopamine, helping to replenish the body's diminished dopamine levels in conjunction with the effects of mannitol.
Mannitol Powder
Contains 10% Mucuna
Natural Effective Treatment
No side effects
Safe, Tested & Proven
Relieve Symptoms
"Parkinson's patients who consume Mannitol, report improvements in both motor and non-motor symptoms".
People Like You
Tania D. Barrie, CA
"I'm taking one teaspoon a day for the last 3 months and I'm getting better every day, although it is a slow improvement. I got my voice back, can speak loud and clear, There was a radical improvement in the quality of my sleep, and I can now use less medication and less Mannitol"
Josh B. Jerusalem, Israel
"Listen, this Mannitol powder saved my life. Before using it, I used costly medications which had side effects and I was really depressed, After using your Mannitol treatment I feel that I want to leave again. My leg pain leg ceased, I got back my smell sense, I could sleep well, and I could finally use fewer medications "
Danny S. FL, USA
"The medications did not help me, but your natural product saved me! I call it "natural cure for parkinson's disease". I feel much better, and I can surely say that this is the best treatment for Parkinson's.
Thanks!!!
Robert K. PA, USA
"I was diagnosed with Parkinson’s and struggled with severe pain in my extremities. I have been on Top Probiotics’s Mannitol product for approximately three months and my pain is largely gone! It appears to me my pain relief is from this product! It has made a major difference in the quality of my life! ALL FOR THE BETTER!!!"
George N. Canada
"I first bought this mannitol about a year ago, and I'm using it since then on a daily basis (3 times a day). Mannitol made me feel vital, my sense of taste improved immeasurably, my sleep is now deep and good, the pain is gone, and the tremors were significantly reduced. I know I have not been cured but thanks to the Mannitol I feel much better. Thank you very much"
Alex M, London, UK
"I purchased the mannitol for my mom and I definitely highly recommend it. It is very helpful in relieving symptoms and relieving pain significantly.
I will buy again and again :-)
Thank you very much !!!
Yuval C. TLV, IL
"To Whom It May Concern,
My dear father had unbearable tremors in his hands mainly while eating. We tried almost everything to solve the problem (coconut oil and more ..) until we got this Mannitol.
After several days of using it, to our surprise, the tremors stopped.
After about 3 months of use, we stopped taking the Mannitol, but after a few weeks, the tremors gradually returned.
We decided to take the Mannitol again and resolved the hand tremors issue".
Ray F. Ohio, USA
"I purchased the mannitol for my mom and I definitely highly recommend it. It is very helpful in relieving symptoms and relieving pain significantly.
I will buy again and again :-)
Thank you very much !!!
Success!
While medications typically cannot penetrate the blood-brain barrier, researchers recommend using mannitol alongside other approved treatments due to its proven ability to cross this barrier. Mannitol facilitates the passage of beneficial compounds from established medications, enhancing the effectiveness of Parkinson's disease treatment.
Many people have already reported improvements in their symptoms through the use of mannitol.
Directions: Take 2 teaspoons daily (approximately 10 grams).
Easy to use: Mannitol can be mixed with both hot and cold beverages.
300 gr.
48.90US$​
600 gr.
88.90US$​
900 gr.
119.90US$​
Despite the situation in Israel, we continue shipping worldwide as usual,
typically arriving within 3-5 business days
Ingredients:
Our unique Mannitol powder formula includes 10% Mucuna pruriens.
It comes in a special PET jar designed to prevent exposure to radiation and moisture.
Net Wt: 300g (10.6 oz)
Mannitol
What is Mannitol?
Mannitol, a natural sugar alcohol, has recently been proposed as a potential disease-modifying agent for Parkinson's disease. In animal models, mannitol interferes with the formation of α-synuclein fibrils, inhibits α-synuclein oligomer formation, and contributes to the phenotypic recovery of impaired motor functions. Patients with Parkinson's who consume mannitol report improvements in both motor and non-motor symptoms. However, the safety of long-term oral mannitol use, the tolerable dose, and its potential benefits have not been clinically studied.
To address this gap, we conducted a phase IIa, randomized, double-blind, placebo-controlled, single-center, dose-escalating study (ClinicalTrials.gov Identifier: NCT03823638) to evaluate the safety of oral mannitol in Parkinson's disease and determine the maximal tolerable oral dose. The study lasted 36 weeks and included four dose escalations of oral mannitol or dextrose, reaching a maximum dose of 18 g per day. The primary outcome was the safety of oral mannitol, assessed by the number of adverse events and abnormal laboratory results. While clinical and biochemical efficacy measures were collected, they were not statistically powered.
Fourteen patients receiving mannitol completed the trial, in addition to eight patients on placebo. No severe mannitol-related adverse events were observed. However, gastrointestinal symptoms limited dose escalation in 6 out of 14 participants on mannitol. None of the clinical or biochemical secondary outcome measures significantly differed between the groups.
We concluded that long-term use of 18 g per day of oral mannitol is safe for Parkinson's disease patients, though only two-thirds of patients tolerated this maximal dose. These findings should be considered in the design of future efficacy studies.
Mucuna
What is Mucuna Pruriens (MP)?
Mucuna pruriens, commonly known as the velvet bean, is a legume that thrives in tropical and subtropical regions around the world, including Africa, Asia, the Caribbean, and the Pacific Islands. While the beans can be consumed as food after boiling, MP is also recognized as a medicinal plant, used for millennia in traditional Ayurvedic Indian medicine to treat a variety of conditions. Research has explored MP for its anti-diabetic, antimicrobial, antioxidant, antiepileptic, and antidepressant properties, among others. Notably, Mucuna pruriens contains 6-9% levodopa by weight, making it particularly valuable in alleviating parkinsonian symptoms.
Mucuna pruriens can enhance the effectiveness of mannitol in managing Parkinson's disease symptoms; while mannitol helps to reduce the formation of toxic α-synuclein aggregates in the brain, Mucuna pruriens provides a natural source of levodopa, a precursor to dopamine. This is crucial since Parkinson's disease is characterized by a deficiency of dopamine in the brain. By increasing dopamine levels, Mucuna pruriens can work synergistically with mannitol, potentially improving both motor and non-motor symptoms for individuals living with Parkinson's disease.
Mucuna | Velvet Bean
Professional Articles About Mannitol
“it acts as a molecular chaperone — a type of molecule that recognizes misfolded proteins and either shepherds them toward cellular waste disposal pathways, or initiates a refolding response."
“A Blood-Brain Barrier (BBB) Disrupter Is Also a Potent α-Synuclein (α-syn) Aggregation Inhibitor
A Novel Dual mechanism of
Mannitol for the treatment of Parkinson disease (PD)”
“56% report improvement in their Parkinson's symptoms”
”Patients show greater improvement the longer they took Mannitol"
(Clinicrowd Webinar, March, 25th, 2018)
Why is it so important to add Brain-770 along with Mannitol?
While Mannitol helps prevent the formation of α-synuclein protein clumps, Brain-770 can dissolve and eliminate clumps that have already formed. This is why we highly recommend Brain-770 as a valuable supplement not only for managing Parkinson's disease but also for enhancing overall brain health.
Brain-770 is composed of multiple components specifically tailored to enhance the activity and functionality of the pineal gland, mitigate calcification, and hinder the crystallization of α-synuclein protein, which obstructs dopamine passage to the brain's gray matter. By significantly enhancing memory and improving overall quality of life, Brain-770 serves as a potential treatment and preventive measure against conditions such as Alzheimer's disease, dementia, sclerosis, and Parkinson's disease.
120 Capsules
95.00$ 88.90$
Mannitol Reviews
4.7 ★★★★★
32 REVIEWS
Product Reviews
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Pamela Lamattina
5 ★★★★★
purchased for my husband who has Parkinsons and it does seem to help with the various conditions PD
exhibits. My husband has Parkinsons and it took about 5 months before we noticed a change but we do. The tremors are not as bad , he is not as foggy and not as depressed as he was before starting this product . He continues to take 2 doses a day. Will post an update when he starts the new product.
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Sharon Johnson
5 ★★★★★
Never expected to get product this fast. Service and delivery was excellent!
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Fred Okoduwa
4 ★★★★
Appears to have some good effect,may require long term use to get optimal effects.So will keep using for now.Very good customer/delivery service. Thanks.
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Charles Guarisco
5 ★★★★★
Excellent! My husband takes it for Parkinsonism tremors. So far we haven't noticed a decrease in the tremors. He still likes it though, because it helps him go to the bathroom easier in the morning. He wants to continue to take it to see if he gets results. The video we saw when we first looked into it said to "be patient" because it can take several months of taking this to see results.
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Daniel M.
4 ★★★★
I have been using your product for over two months. I can't say that the product eliminated all the symptoms of the disease, but it definitely eased them, and that's why I continue to use it.
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Paul V.
5 ★★★★★
Highly recommend. I sleep better, I suffer less pain and there is even a slight improvement in tremors. Thanks. Highly recommend
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Carol B.
5 ★★★★★
My husband really likes this mannitol. He says it helps him. I can testify that his speech has definitely improved recently
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Krishna Natarajan
5 ★★★★★
Highly recommended! It works as advertised
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Christian N
5 ★★★★★
I was surprised with the positive results. I take it with my tea, and it helped with my tremors, with the pain, and with my sleep. Very recommended
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Judith Smith
5 ★★★★★
Fantastic!
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Christine Pratt
4 ★★★★
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Constance C.
5 ★★★★★
Just wanted to let you know that my husband has been taking the Mannitol/ Mucuna powder for several months now, and has significantly improved his quality of sleep. He has REM Sleep disorder, and takes a spoonful before bed every evening. He has a hand tremor, and has been told by a neurologist he may develop Parkinson's over the next 5 years. We wanted to be proactive, so I went online and found your product. We have been very happy about the results! He went from thrashing about and acting out his dreams 3 times per month, to once every other month- and now it is much milder when it does happen. We are very happy with your product and hope that it can provide some measure of slowing down the onset of Parkinson's. thank you very much!
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Izabela C.
5 ★★★★★
Very good!
Christopher R.
4 ★★★★
I'm satisfied
I'm taking it for a while, and I feel a slight improvement (Which is very satisfying for me). Hope it will get even better soon.
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Joseph O.
5 ★★★★★
I Recommend this Mannitol
Barry
5 ★★★★★
Expensive but good! I don’t like that I should pay import duties In Canada every time I'm ordering it, but I do like the product – It reduced my symptoms.
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Mia C.
4 ★★★★
I bought it to my grandma 3 weeks ago– She likes it & it seems that she's having a physical improvement.
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Lucas W.
2 ★★
Not so satisfied. Took a whole jar and felt only slight improvement.
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Benjamin S.
5 ★★★★★
Exactly as described, high quality, fast delivery. Good!
Amelia R.
4 ★★★★
I think it helped me to stop the worsening processes of the disease. I have been taking Mannitol for a few weeks now, and I feel a bit better, and there is no further deterioration in my condition. I think it is the best I can do now, and I like it.
Josh T.
5 ★★★★★
Excellent!
Highly recommended! It helped me a lot.
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Miriam G.
5 ★★★★★
This is a good quality product. I've been trying some other before, but this one is the best I had. Very recommended, and very helpful. My day to day life feels much better.
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Oren C.
5 ★★★★★
Recommended!
I order this product regularly - very good! I'm having it with my Coffee.
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Jerry B.
5 ★★★★★
Good product, I like it, excellent customer support, Thanks!
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Michael E
5 ★★★★★
Arrived fast, and it has Mucuna inside, so results are a bit faster. I'm satisfied.
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Max H.
5 ★★★★★
I am a repeat customer, and overtime the treatment has been helpful.
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Michael E
5 ★★★★★
Arrived fast, and it has Mucuna inside, so results are a bit faster. I'm satisfied.
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Jasmin A.
5 ★★★★★
My husband uses this Mannitol to reduce his Parkinson's symptoms. I can see an improvement with his sleep and voice, and maybe a bit with his tremor. He likes it, and seems to work for him.
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Evelyn
3 ★★★
Not sure yet. I'm taking this product for 2 weeks now and it is almost like every natural sweetener – Easy to use, I like it. I didn't feel any improvement yet, but according to the studies I've read, it might take a while. Hope to update soon
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Tim A.
5 ★★★★★
Certainly helped me
I've been taking this Mannitol for a few months, so far, I find it very helpful.
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George
5 ★★★★★
I first bought this mannitol about a year ago, and I'm using it since then on a daily basis (3 times a day). Mannitol made me feel vital, my sense of taste improved immeasurably, my sleep is now deep and good, the pain is gone, and the tremors were significantly reduced. I know I have not been cured but thanks to this Mannitol I feel much better. Thank you very much
Robert N.
5 ★★★★★
I was diagnosed with Parkinson’s and struggled with severe pain in my extremities. I have been on Top-Probiotics Mannitol product for approximately three months and my pain is largely gone! It appears to me that my pain relief is from this product! It has made a major difference in the quality of my life! ALL FOR THE BETTER!!!
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David V
5 ★★★★★
I've been taking Mannitol for 10 weeks. At the first 4 weeks, I've got relief from going to the toilets. At the next few weeks, my voice became clearer and loud. The Mannitol helped me, but you have to be patience for getting results.
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How do I use Helico Bacstop?Take 2 capsules daily - one in the morning and one in the evening, on an empty stomach. For best results, take them 60 minutes before a meal or 2 hours after eating.
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How will I know if HelicoBacstop is helping me?You should start noticing improvements in symptoms such as heartburn, abdominal pain, and reflux within a few weeks of regular use, though results may vary. Many users report feeling better in just a few weeks, but for optimal results, it's recommended to continue the regimen for at least 2 months. Additionally, we suggest doing a breath test about a month after completing the treatment to assess the effectiveness.
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Will I feel any improvement by using Helico-Bacstop?Yes! HelicoBacstop reduces Helicobacter pylori by up to 80%, bringing it down to its minimal, necessary amount. You should feel much better once using Helico-Bacstop.
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Can I eat everything while taking Helico-Bacstop?For the best results, it's recommended to avoid certain foods during and right after treatment, including pastries, fried foods, smoked foods, dairy products, white flour bread, and tomatoes. These foods may interfere with the effectiveness of the treatment.
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How long does it take to Helico-Bacstop to start working?Within a few days of starting HelicoBacstop, you should begin to feel much better, with symptoms improving noticeably. Most users experience positive changes within the first few days.
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Can I take Helico Bacstop along, or after taking Antibiotics"Yes, HelicoBacstop can be taken alongside or after completing a course of antibiotics. In fact, taking it after antibiotics may help restore balance to your gut flora and support overall digestive health. However, according to the World Health Organization (WHO) in 2017, Helicobacter pylori has developed resistance to many common antibiotics, making them less effective as a treatment. This is why the WHO advises against relying solely on antibiotics for H. pylori eradication. For optimal results, it’s worth considering natural remedies like HelicoBacstop, which may offer an alternative approach. As always, consult with your healthcare provider to determine the best course of action for your specific needs.
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Are there any side effects?Helico-Bacstop is a natural remedy with no known side effects when used as directed. However, if you have any underlying health conditions, it’s always a good idea to consult with a healthcare professional before starting any new supplement.
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How should I store HelicoBacstop?HelicoBacstop should be stored in a cool, dry place, away from direct sunlight. It does not require refrigeration. Simply keep the bottle tightly closed to protect the capsules from moisture and light, ensuring they maintain their potency.
About US
Mannitol is manufactured by Homeotreat Lab, an Israeli company specializing in the development of natural and effective products since 1997. Homeotreat Lab provides a wide range of natural solutions designed to improve quality of life. Both research and development, as well as production and packaging, take place in Israel.
The company places a strong emphasis on product quality and development processes, investing significant resources in thorough research and the selection of high-quality raw materials. All manufacturing and packaging processes adhere to GMP and ISO certifications, under the supervision of the Israeli Ministry of Health.
Shipping
We ship worldwide.
All our products are shipped from Israel using an expedited/express shipping service, with delivery usually taking 3-6 business days. Shipping fees will be calculated at checkout.
Please allow up to 2 business days for handling time.
Kindly note that packages sent to customers outside of the United States may incur customs fees upon arrival in the recipient's country.
We are not responsible for any delays or duties imposed by customs in the recipient's country.
Contact Us
IF you have any questions regarding Mannitol (Parkinson's treatment), please don't hesitate to contact us:
Disclaimer: The information presented on this website originates from the manufacturer and remains their sole responsibility. It should not be construed as medical advice or recommendation. The information provided here is for informational purposes only and should not be relied upon for diagnosing or treating any health condition or for prescribing medications or other forms of treatment.
Prior to initiating any diet, exercise, or supplementation regimen, or before taking any medication, it is recommended that you seek advice from a qualified healthcare professional. If you have or suspect you have a health issue, consulting a healthcare professional is advisable.
Neither Top-probiotics.com nor the US Food and Drug Administration has evaluated the products listed on this website.